Maternal Nodal inversely affects NODAL and STOX1 expression in the fetal placenta

Maternal Nodal inversely affects NODAL and STOX1 expression in the fetal placenta

Nodal, a secreted signaling protein from the TGFβ-super family plays a vital role during early embryonic development. Recently, it was found that maternal decidua-specific Nodal knockout mice show intrauterine growth restriction (IUGR) and preterm birth. As the chromosomal location of NODAL is in th...

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Bibliographic Details
Main Authors: Hari Krishna Thulluru, Craig ePark, Daniel eDufort, Gunilla eKleiverda, Cees eOudejans, Marie eVan Dijk
Format: Article
Language:English
Published: Frontiers Media S.A. 2013-08-01
Series:Frontiers in Genetics
Subjects:
Decidua
Pre-Eclampsia
Nodal
extravillous trophoblast
STOX1
Online Access:http://journal.frontiersin.org/Journal/10.3389/fgene.2013.00170/full

Internet

http://journal.frontiersin.org/Journal/10.3389/fgene.2013.00170/full

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