Development of Apoptotic-Cell-Inspired Antibody–Drug Conjugate for Effective Immune Modulation

Background: Apoptotic cells’ phosphoserine (PS) groups have a significant immunosuppressive effect. They inhibit proinflammatory signals by interacting with various immune cells, including macrophages, dendritic cells, and CD4<sup>+</sup> cells. Previously, we synthesized PS-group-immobi...

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Bibliographic Details
Main Authors: Gyeongwoo Lee, Taishu Iwase, Shunsuke Matsumoto, Ahmed Nabil, Mitsuhiro Ebara
Format: Article
Language:English
Published: MDPI AG 2023-11-01
Series:International Journal of Molecular Sciences
Subjects:
Online Access:https://www.mdpi.com/1422-0067/24/22/16036