Genotyping in the MHC locus: potential for defining predictive markers in sarcoidosis

<p>Abstract</p> <p>In sarcoidosis, host genetic factors are discussed as contributing to disease susceptibility and course. Since tumor necrosis factor (TNF)-α is a central mediator of granuloma formation and since elevated TNF-α levels are found during active phases of sarcoidosis...

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Bibliographic Details
Main Authors: Seitzer Ulrike, Gerdes Johannes, Müller-Quernheim Joachim
Format: Article
Language:English
Published: BMC 2001-10-01
Series:Respiratory Research
Subjects:
Online Access:http://dx.doi.org/10.1186/rr178