Pilot testing and optimization of a larval fathead minnow high throughput transcriptomics assay

Pilot testing and optimization of a larval fathead minnow high throughput transcriptomics assay

Concentrations at which global gene expression profiles in cells or animals exposed to a test substance start to differ significantly from those of controls have been proposed as an alternative point of departure for use in screening level hazard assessment. The present study describes pilot testing...

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Bibliographic Details
Main Authors: Daniel L. Villeneuve, Michelle Le, Monique Hazemi, Adam Biales, David C. Bencic, Kendra Bush, Robert Flick, John Martinson, Mackenzie Morshead, Kelvin Santana Rodriguez, Kelsey Vitense, Kevin Flynn
Format: Article
Language:English
Published: Elsevier 2023-01-01
Series:Current Research in Toxicology
Subjects:
Computational toxicology
Benchmark dose
ECOTOX knowledgebase
Fish
RNA sequencing
Transcriptomics-based point of departure
Online Access:http://www.sciencedirect.com/science/article/pii/S2666027X22000366

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http://www.sciencedirect.com/science/article/pii/S2666027X22000366

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