The Effect of Organoselenium Compounds on Histone Deacetylase Inhibition and Their Potential for Cancer Therapy

The Effect of Organoselenium Compounds on Histone Deacetylase Inhibition and Their Potential for Cancer Therapy

Genetic and epigenetic changes alter gene expression, contributing to cancer. Epigenetic changes in cancer arise from alterations in DNA and histone modifications that lead to tumour suppressor gene silencing and the activation of oncogenes. The acetylation status of histones and non-histone protein...

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Bibliographic Details
Main Authors: Theolan Adimulam, Thilona Arumugam, Ashmika Foolchand, Terisha Ghazi, Anil A. Chuturgoon
Format: Article
Language:English
Published: MDPI AG 2021-11-01
Series:International Journal of Molecular Sciences
Subjects:
cancer
organoselenium compounds
selenomethionine
selenocysteine
methylselenocysteine
histone deacetylation
Online Access:https://www.mdpi.com/1422-0067/22/23/12952

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https://www.mdpi.com/1422-0067/22/23/12952

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