Development and function of CD94-deficient natural killer cells.

Development and function of CD94-deficient natural killer cells.

The CD94 transmembrane-anchored glycoprotein forms disulfide-bonded heterodimers with the NKG2A subunit to form an inhibitory receptor or with the NKG2C or NKG2E subunits to assemble a receptor complex with activating DAP12 signaling proteins. CD94 receptors expressed on human and mouse NK cells and...

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Bibliographic Details
Main Authors: Mark T Orr, Jun Wu, Min Fang, Luis J Sigal, Pieter Spee, Thomas Egebjerg, Erik Dissen, Sigbjørn Fossum, Joseph H Phillips, Lewis L Lanier
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2010-12-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC2997080?pdf=render

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http://europepmc.org/articles/PMC2997080?pdf=render

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