Cognitive function in very old men does not correlate to biomarkers of Alzheimer’s disease

Cognitive function in very old men does not correlate to biomarkers of Alzheimer’s disease

Abstract Background The Alzheimer’s disease (AD) brain displays atrophy with amyloid-β (Aβ) and tau deposition, whereas decreased Aβ42 and increased tau are measured in cerebrospinal fluid (CSF). The aim of this study was to relate cognitive performance to the degree of brain atrophy, CSF biomarker...

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Bibliographic Details
Main Authors: V. Velickaite, V. Giedraitis, K. Ström, I. Alafuzoff, H. Zetterberg, L. Lannfelt, L. Kilander, E-M. Larsson, M. Ingelsson
Format: Article
Language:English
Published: BMC 2017-09-01
Series:BMC Geriatrics
Subjects:
Brain atrophy
Cognitive performance
CSF biomarkers
Neuropathology
AD biomarkers
Advanced age
Online Access:http://link.springer.com/article/10.1186/s12877-017-0601-6

Internet

http://link.springer.com/article/10.1186/s12877-017-0601-6

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