NSP6 inhibits the production of ACE2-containing exosomes to promote SARS-CoV-2 infectivity

NSP6 inhibits the production of ACE2-containing exosomes to promote SARS-CoV-2 infectivity

ABSTRACT The emergence of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has triggered a global pandemic, which severely endangers public health. Our and others’ works have shown that the angiotensin-converting enzyme 2 (ACE2)-containing exosomes (ACE2-exos) have superior antiviral eff...

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Bibliographic Details
Main Authors: Xi Lv, Ran Chen, Taizhen Liang, Haojie Peng, Qiannan Fang, Shiqi Xiao, Sen Liu, Meilin Hu, Fei Yu, Lixue Cao, Yiwen Zhang, Ting Pan, Zhihui Xi, Yao Ding, Linyuan Feng, Tao Zeng, Wenjing Huang, Hui Zhang, Xiancai Ma
Format: Article
Language:English
Published: American Society for Microbiology 2024-03-01
Series:mBio
Subjects:
NSP6
ACE2
exosomes
SARS-CoV-2
CD63
PSMD12
Online Access:https://journals.asm.org/doi/10.1128/mbio.03358-23

Internet

https://journals.asm.org/doi/10.1128/mbio.03358-23

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