Regional hypothermia attenuates secondary-injury caused by time-out application of tourniquets following limb fragments injury combined with hemorrhagic shock

Abstract Background Tourniquet is the most widely used and effective first-aid equipment for controlling hemorrhage of injured limb in battlefield. However, time-out application of tourniquets leads to ischemic-necrosis of skeletal muscles and ischemia-reperfusion injury. Regional hypothermia (RH) o...

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Bibliographic Details
Main Authors: Changmei Weng, Kai Lan, Tao Li, Liangchao Zhang, Jianmin Wang, Xinan Lai
Format: Article
Language:English
Published: BMC 2019-11-01
Series:Scandinavian Journal of Trauma, Resuscitation and Emergency Medicine
Subjects:
Online Access:http://link.springer.com/article/10.1186/s13049-019-0678-3