Anti CD38 monoclonal antibodies for multiple myeloma treatment

CD38 is a transmembrane glycoprotein with ectoenzymatic activity and is highly and uniformly expressed on multiple myeloma (MM) cells. CD38 is expressed also at relatively low levels on normal lymphoid and myeloid cells, and in some tissues of non-hematopoietic origin. The specificity of this target...

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Bibliographic Details
Main Authors: Alessandro Gozzetti, Sara Ciofini, Martina Simoncelli, Adele Santoni, Paola Pacelli, Donatella Raspadori, Monica Bocchia
Format: Article
Language:English
Published: Taylor & Francis Group 2022-11-01
Series:Human Vaccines & Immunotherapeutics
Subjects:
Online Access:http://dx.doi.org/10.1080/21645515.2022.2052658