Poly(I:C) enhances mesenchymal stem cell control of myeloid cells from COVID-19 patients

Summary: Mesenchymal stem cells (MSCs) are being studied for the treatment of COVID-19-associated critical illness, due to their immunomodulatory properties. Here, we hypothesized that viral mimic-priming improves MSCs’ abilities to rebalance the dysregulated immune responses in COVID-19. Transcript...

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Bibliographic Details
Main Authors: Luciana Souza-Moreira, Yuan Tan, Yan Wang, Jia-Pey Wang, Mahmoud Salkhordeh, Jennifer Virgo, Maria Florian, Aidan B.P. Murray, Irene Watpool, Lauralyn McIntyre, Shane English, Duncan J. Stewart, Shirley H.J. Mei
Format: Article
Language:English
Published: Elsevier 2022-05-01
Series:iScience
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2589004222004588