Dietary antigens suppress the proliferation of type 2 innate lymphoid cells by restraining homeostatic IL-25 production

Dietary antigens suppress the proliferation of type 2 innate lymphoid cells by restraining homeostatic IL-25 production

Abstract Dietary antigens affect the adaptive immunity of the host by inducing regulatory T cells and IgE-producing B cells. However, their roles in innate immune compartments such as innate lymphoid cells (ILCs) and intestinal epithelial cells (IECs) are unclear. Here, using antigen-free (AF) mice,...

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Bibliographic Details
Main Authors: Minji Lee, Hyun-Ja Ko, Sung-Wook Hong, Jungeun Park, Seokjin Ham, Mingyu Kim, Dong-il Kwon, Myeong-seok Lee, Tae-Young Roh, Kwang Soon Kim, You Jeong Lee
Format: Article
Language:English
Published: Nature Portfolio 2022-05-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-022-11466-4

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https://doi.org/10.1038/s41598-022-11466-4

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