α‐Synuclein aggregation causes muscle atrophy through neuromuscular junction degeneration

α‐Synuclein aggregation causes muscle atrophy through neuromuscular junction degeneration

Abstract Background Sarcopenia is common in patients with Parkinson's disease (PD), showing mitochondrial oxidative stress in skeletal muscle. The aggregation of α‐synuclein (α‐Syn) to induce oxidative stress is a key pathogenic process of PD; nevertheless, we know little about its potential ro...

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Bibliographic Details
Main Authors: Qiumei Yang, Yanyan Wang, Chunsong Zhao, Shimin Pang, Jing Lu, Piu Chan
Format: Article
Language:English
Published: Wiley 2023-02-01
Series:Journal of Cachexia, Sarcopenia and Muscle
Subjects:
Area
Parkinson's disease
Muscle atrophy
Oxidative stress
Neuromuscular junction
α‐Synuclein
Online Access:https://doi.org/10.1002/jcsm.13123

Internet

https://doi.org/10.1002/jcsm.13123

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