Design, Synthesis and Evaluation of New Indolylpyrimidylpiperazines for Gastrointestinal Cancer Therapy

Design, Synthesis and Evaluation of New Indolylpyrimidylpiperazines for Gastrointestinal Cancer Therapy

Human A<sub>3</sub> adenosine receptor hA<sub>3</sub>AR has been implicated in gastrointestinal cancer, where its cellular expression has been found increased, thus suggesting its potential as a molecular target for novel anticancer compounds. Observation made in our previous...

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Bibliographic Details
Main Authors: Aaron Tan, Maria V. Babak, Gopalakrishnan Venkatesan, Clarissa Lim, Karl-Norbert Klotz, Deron Raymond Herr, Siew Lee Cheong, Stephanie Federico, Giampiero Spalluto, Wei-Yi Ong, Yu Zong Chen, Jason Siau Ee Loo, Giorgia Pastorin
Format: Article
Language:English
Published: MDPI AG 2019-10-01
Series:Molecules
Subjects:
gastrointestinal cancer
ha<sub>3</sub>ar
partial agonists
indolylpyrimidylpiperazines
Online Access:https://www.mdpi.com/1420-3049/24/20/3661

Internet

https://www.mdpi.com/1420-3049/24/20/3661

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