Novel pre-clinical mouse models for chronic Graft-versus-Host Disease

Novel pre-clinical mouse models for chronic Graft-versus-Host Disease

Despite considerable progress in allogeneic hematopoietic cell transplantation (allo-HCT) has been achieved over the past years, chronic Graft-versus-Host Disease (cGvHD) still contributes to high morbidity rates, thus remaining a major hurdle in allo-HCT patients. To understand the complex pathophy...

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Bibliographic Details
Main Authors: Lydia Verlaat, Katarina Riesner, Martina Kalupa, Beate Jung, Sarah Mertlitz, Constanze Schwarz, Jörg Mengwasser, Claudine Fricke, Olaf Penack
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-01-01
Series:Frontiers in Immunology
Subjects:
allogeneic hematopoietic stem cell transplantation
chronic Graft-versus-Host Disease
mouse models
G-CSF
xenogeneic transplantation
fibrosis
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2022.1079921/full

Internet

https://www.frontiersin.org/articles/10.3389/fimmu.2022.1079921/full

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