Bronchus-associated lymphoid tissue (BALT) and survival in a vaccine mouse model of tularemia.
Francisella tularensis causes severe pulmonary disease, and nasal vaccination could be the ideal measure to effectively prevent it. Nevertheless, the efficacy of this type of vaccine is influenced by the lack of an effective mucosal adjuvant.Mice were immunized via the nasal route with lipopolysacch...
Main Authors: | , , , , , , , , |
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Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2010-06-01
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Series: | PLoS ONE |
Online Access: | http://europepmc.org/articles/PMC2886834?pdf=render |