Bronchus-associated lymphoid tissue (BALT) and survival in a vaccine mouse model of tularemia.

Francisella tularensis causes severe pulmonary disease, and nasal vaccination could be the ideal measure to effectively prevent it. Nevertheless, the efficacy of this type of vaccine is influenced by the lack of an effective mucosal adjuvant.Mice were immunized via the nasal route with lipopolysacch...

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Bibliographic Details
Main Authors: Damiana Chiavolini, Javier Rangel-Moreno, Gretchen Berg, Kate Christian, Laura Oliveira-Nascimento, Susan Weir, Joseph Alroy, Troy D Randall, Lee M Wetzler
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2010-06-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC2886834?pdf=render