Sequestration of Voriconazole and Vancomycin Into Contemporary Extracorporeal Membrane Oxygenation Circuits: An in vitro Study

Sequestration of Voriconazole and Vancomycin Into Contemporary Extracorporeal Membrane Oxygenation Circuits: An in vitro Study

Background: Bacterial and fungal infections are common and often contribute to death in patients undergoing extracorporeal membrane oxygenation (ECMO). Drug disposition is altered during ECMO, and adsorption in the circuit is an established causative factor. Vancomycin and voriconazole are widely us...

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Bibliographic Details
Main Authors: Genny Raffaeli, Giacomo Cavallaro, Karel Allegaert, Birgit C. P. Koch, Fabio Mosca, Dick Tibboel, Enno D. Wildschut
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-08-01
Series:Frontiers in Pediatrics
Subjects:
extracorporeal membrane oxygenation
pharmacokinetics
pharmacology
antibiotics
infection
antifungals
Online Access:https://www.frontiersin.org/article/10.3389/fped.2020.00468/full

Internet

https://www.frontiersin.org/article/10.3389/fped.2020.00468/full

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