Recurrent gastrointestinal hemorrhage in treatment with dasatinib in a patient showing SMAD4 mutation with acute lymphoblastic leukemia Philadelphia positive and juvenile polyposis hereditary hemorrhagic telangiectasia syndrome

Recurrent gastrointestinal hemorrhage in treatment with dasatinib in a patient showing SMAD4 mutation with acute lymphoblastic leukemia Philadelphia positive and juvenile polyposis hereditary hemorrhagic telangiectasia syndrome

We report a case of a patient affected by juvenile polyposis and hereditary hemorrhagic telangiectasia linked to a <em>SMAD4</em> mutation who developed acute lymphoblastic leukemia positive for the Philadelphia chromosome translocation and with a complex karyotype. During the treatment...

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Détails bibliographiques
Auteurs principaux: Chiara Sartor, Cristina Papayannidis, Maria Chiara Abbenante, Ilaria Iacobucci, Alessandro Broccoli, Claudia Venturi, Nicoletta Testoni, Anna Ferrari, Giovanni Martinelli
Format: Article
Langue:English
Publié: MDPI AG 2013-07-01
Collection:Hematology Reports
Sujets:
juvenile poyposis, hereditary hemorrhagic telangiectasia, acute lymphoblastic leukemia, SMAD4, Philadelphia chromosome, dasatinib, hemorrhage
Accès en ligne:http://www.pagepress.org/journals/index.php/hr/article/view/4800

Internet

http://www.pagepress.org/journals/index.php/hr/article/view/4800

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