Natural Activators of Autophagy Increase Maximal Walking Distance and Reduce Oxidative Stress in Patients with Peripheral Artery Disease: A Pilot Study

Natural Activators of Autophagy Increase Maximal Walking Distance and Reduce Oxidative Stress in Patients with Peripheral Artery Disease: A Pilot Study

Trehalose, spermidine, nicotinamide, and polyphenols have been shown to display pro-autophagic and antioxidant properties, eventually reducing cardiovascular and ischemic complications. This study aimed to investigate whether a mixture of these components improves maximal walking distance (MWD) in p...

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Bibliographic Details
Main Authors: Ombretta Martinelli, Mariangela Peruzzi, Simona Bartimoccia, Alessandra D’Amico, Simona Marchitti, Speranza Rubattu, Giovanni Alfonso Chiariello, Luca D’Ambrosio, Sonia Schiavon, Fabio Miraldi, Wael Saade, Mizar D’Abramo, Annachiara Pingitore, Lorenzo Loffredo, Cristina Nocella, Maurizio Forte, Pasquale Pignatelli
Format: Article
Language:English
Published: MDPI AG 2022-09-01
Series:Antioxidants
Subjects:
autophagy
oxidative stress
peripheral artery disease
trehalose
polyphenols
Online Access:https://www.mdpi.com/2076-3921/11/9/1836

Internet

https://www.mdpi.com/2076-3921/11/9/1836

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