New small molecules targeting apoptosis and cell viability in osteosarcoma.

Despite the option of multimodal therapy in the treatment strategies of osteosarcoma (OS), the most common primary malignant bone tumor, the standard therapy has not changed over the last decades and still involves multidrug chemotherapy and radical surgery. Although successfully applied in many pat...

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Bibliographic Details
Main Authors: Doris Maugg, Ina Rothenaigner, Kenji Schorpp, Harish Kumar Potukuchi, Eberhard Korsching, Daniel Baumhoer, Kamyar Hadian, Jan Smida, Michaela Nathrath
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4454490?pdf=render