A novel circ_MACF1/miR-942-5p/TGFBR2 axis regulates the functional behaviors and drug sensitivity in gefitinib-resistant non-small cell lung cancer cells

A novel circ_MACF1/miR-942-5p/TGFBR2 axis regulates the functional behaviors and drug sensitivity in gefitinib-resistant non-small cell lung cancer cells

Abstract Background Resistance to gefitinib remains a major obstacle for the successful treatment of non-small cell lung cancer (NSCLC) with epidermal growth factor receptor (EGFR) mutations. In this paper, we studied the precise actions of circular RNA (circRNA) microtubule actin crosslinking facto...

Full description

Bibliographic Details
Main Authors: Daping Fan, Yue Yang, Wei Zhang
Format: Article
Language:English
Published: BMC 2022-01-01
Series:BMC Pulmonary Medicine
Subjects:
Gefitinib resistance
NSCLC
circ_MACF1
miR-942-5p
TGFBR2
Online Access:https://doi.org/10.1186/s12890-021-01731-z

Internet

https://doi.org/10.1186/s12890-021-01731-z

Similar Items