Interplay between Endoplasmic Reticulum Stress and Large Extracellular Vesicles (Microparticles) in Endothelial Cell Dysfunction

Interplay between Endoplasmic Reticulum Stress and Large Extracellular Vesicles (Microparticles) in Endothelial Cell Dysfunction

Upon increased demand for protein synthesis, accumulation of misfolded and/or unfolded proteins within the endoplasmic reticulum (ER), a pro-survival response is activated termed unfolded protein response (UPR), aiming at restoring the proper function of the ER. Prolonged activation of the UPR leads...

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Bibliographic Details
Main Authors: Aisha Osman, Tarek Benameur, Hesham M. Korashy, Asad Zeidan, Abdelali Agouni
Format: Article
Language:English
Published: MDPI AG 2020-10-01
Series:Biomedicines
Subjects:
extracellular vesicles (EVs)
microparticles (MPs)
endoplasmic reticulum (ER) stress
endothelial dysfunction
cardiovascular disease
diabetes
Online Access:https://www.mdpi.com/2227-9059/8/10/409

Internet

https://www.mdpi.com/2227-9059/8/10/409

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