Correlation of memory T cell responses against TRAP with protection from clinical malaria, and CD4 CD25 high T cells with susceptibility in Kenyans.

Correlation of memory T cell responses against TRAP with protection from clinical malaria, and CD4 CD25 high T cells with susceptibility in Kenyans.

Immunity to malaria develops naturally in endemic regions, but the protective immune mechanisms are poorly understood. Many vaccination strategies aim to induce T cells against diverse pre-erythrocytic antigens, but correlates of protection in the field have been limited. The objective of this study...

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Bibliographic Details
Main Authors: Stephen M Todryk, Philip Bejon, Tabitha Mwangi, Magdalena Plebanski, Britta Urban, Kevin Marsh, Adrian V S Hill, Katie L Flanagan
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2008-04-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC2323567?pdf=render

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http://europepmc.org/articles/PMC2323567?pdf=render

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