Clofazimine-Mediated, Age-Related Changes in Skeletal Muscle Mitochondrial Metabolites

Mitochondrial health declines with age, and older patients can demonstrate dysfunction in mitochondrial-rich tissues, such as cardiac and skeletal muscle. Aged mitochondria may make older adults more susceptible to adverse drug reactions (ADRs). We assessed mitochondrial metabolic function by measur...

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Bibliographic Details
Main Authors: Jennifer Diaz-Espinosa, Kathleen A. Stringer, Gus R. Rosania
Format: Article
Language:English
Published: MDPI AG 2023-05-01
Series:Metabolites
Subjects:
Online Access:https://www.mdpi.com/2218-1989/13/5/671