White matter hyperintensities are more highly associated with preclinical Alzheimer's disease than imaging and cognitive markers of neurodegeneration

White matter hyperintensities are more highly associated with preclinical Alzheimer's disease than imaging and cognitive markers of neurodegeneration

Abstract Introduction Cognitive tests and nonamyloid imaging biomarkers do not consistently identify preclinical AD. The objective of this study was to evaluate whether white matter hyperintensity (WMH) volume, a cerebrovascular disease marker, is more associated with preclinical AD than conventiona...

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Bibliographic Details
Main Authors: Benjamin M. Kandel, Brian B. Avants, James C. Gee, Corey T. McMillan, Guray Erus, Jimit Doshi, Christos Davatzikos, David A. Wolk, Alzheimer's Disease Neuroimaging Initiative
Format: Article
Language:English
Published: Wiley 2016-01-01
Series:Alzheimer’s & Dementia: Diagnosis, Assessment & Disease Monitoring
Subjects:
Alzheimer's disease
Aging
MRI
PET
White matter
Leukoaraiosis
Online Access:https://doi.org/10.1016/j.dadm.2016.03.001

Internet

https://doi.org/10.1016/j.dadm.2016.03.001

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