Platelet-rich plasma attenuates the severity of joint capsule fibrosis following post-traumatic joint contracture in rats

Platelet-rich plasma attenuates the severity of joint capsule fibrosis following post-traumatic joint contracture in rats

Background: Post-traumatic joint contracture (PTJC) mainly manifests as excessive inflammation leading to joint capsule fibrosis. Transforming growth factor (TGF)-β1, a key regulator of inflammation and fibrosis, can promote fibroblast activation, proliferation, migration, and differentiation into m...

Full description

Bibliographic Details
Main Authors: Yuxin Zhang, Zengguang Wang, Chenyu Zong, Xiaoding Gu, Shuai Fan, Lili Xu, Bin Cai, Shenji Lu
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-01-01
Series:Frontiers in Bioengineering and Biotechnology
Subjects:
platelet-rich plasma
post-traumatic joint contracture
joint capsule fibrosis
transforming growth factor-β1
fibroblasts
Online Access:https://www.frontiersin.org/articles/10.3389/fbioe.2022.1078527/full

Internet

https://www.frontiersin.org/articles/10.3389/fbioe.2022.1078527/full

Similar Items