IL-17A deletion reduces sevoflurane-induced neurocognitive impairment in neonatal mice by inhibiting NF-κB signaling pathway

IL-17A deletion reduces sevoflurane-induced neurocognitive impairment in neonatal mice by inhibiting NF-κB signaling pathway

ABSTRACTWe investigated the role of IL-17A in sevoflurane-inducedneurocognitive impairment in neonatal mice. Seventy-two wild-type (WT) and 42 IL-17A knockout (KO) neonatal mice were randomly divided into WT (n = 36), IL-17A−/− (n = 6), sevoflurane (Sev, n = 36), and IL-17A−/− + sevoflurane (IL-17A−...

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Bibliographic Details
Main Authors: Qi Zhang, Yanan Li, Chunping Yin, Mingyang Gao, Jiaxu Yu, Junfei Guo, Xiaohui Xian, Zhiyong Hou, Qiujun Wang
Format: Article
Language:English
Published: Taylor & Francis Group 2022-06-01
Series:Bioengineered
Subjects:
IL-17A
sevoflurane
NF-κB signaling pathway
neuroinflammation
cognitive dysfunction
Online Access:https://www.tandfonline.com/doi/10.1080/21655979.2022.2090608

Internet

https://www.tandfonline.com/doi/10.1080/21655979.2022.2090608

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