Amantadine Combines Astroglial System Xc<sup>−</sup> Activation with Glutamate/NMDA Receptor Inhibition
A glutamate/NMDA receptor (NMDA-R) antagonist, amantadine (AMA) exhibits a broad spectrum of clinically important properties, including antiviral, antiparkinsonian, neuroprotective, neuro-reparative and cognitive-enhancing effects. However, both clinical and pre-clinical studies have demonstrated th...
Main Authors: | Tomosuke Nakano, Toshiki Hasegawa, Dai Suzuki, Eishi Motomura, Motohiro Okada |
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Format: | Article |
Language: | English |
Published: |
MDPI AG
2019-05-01
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Series: | Biomolecules |
Subjects: | |
Online Access: | https://www.mdpi.com/2218-273X/9/5/191 |
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