423 An omega-6-derived eicosanoid negatively regulates platelet reactivity of cardiovascular patients at increased risk for thrombosis

OBJECTIVES/GOALS: This study aimed to investigate the mechanistic effects of the omega-6-derived eicosanoid 12-HETrE on platelets of cardiovascular patients at risk for a recurrent cardiovascular event triggered by thrombosis. 12-HETrE negatively regulates platelet reactivity through binding to the...

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Bibliographic Details
Main Authors: Adriana Yamaguchi, Amanda Prieur, Theodore R. Holman, Nadia R. Sutton, Michael Holinstat
Format: Article
Language:English
Published: Cambridge University Press 2023-04-01
Series:Journal of Clinical and Translational Science
Online Access:https://www.cambridge.org/core/product/identifier/S2059866123004569/type/journal_article