Development of a Well-Characterized Cynomolgus Macaque Model of Marburg Virus Disease for Support of Vaccine and Therapy Development

Development of a Well-Characterized Cynomolgus Macaque Model of Marburg Virus Disease for Support of Vaccine and Therapy Development

Marburg virus (MARV) is a filovirus that can infect humans and nonhuman primates (NHPs), causing severe disease and death. Of the filoviruses, Ebola virus (EBOV) has been the primary target for vaccine and therapeutic development. However, MARV has an average case fatality rate of approximately 50%,...

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Bibliographic Details
Main Authors: Kendra J. Alfson, Yenny Goez-Gazi, Michal Gazi, Ying-Liang Chou, Nancy A. Niemuth, Marc E. Mattix, Hilary M. Staples, Benjamin Klaffke, Gloria F. Rodriguez, Carmen Bartley, Anysha Ticer, Elizabeth A. Clemmons, John W. Dutton, Anthony Griffiths, Gabe T. Meister, Daniel C. Sanford, Chris M. Cirimotich, Ricardo Carrion
Format: Article
Language:English
Published: MDPI AG 2022-08-01
Series:Vaccines
Subjects:
Marburg virus
animal model
animal rule
Online Access:https://www.mdpi.com/2076-393X/10/8/1314

Internet

https://www.mdpi.com/2076-393X/10/8/1314

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