Rapid selection and proliferation of CD133+ cells from cancer cell lines: chemotherapeutic implications.

Cancer stem cells (CSCs) are considered a subset of the bulk tumor responsible for initiating and maintaining the disease. Several surface cellular markers have been recently used to identify CSCs. Among those is CD133, which is expressed by hematopoietic progenitor cells as well as embryonic stem c...

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Bibliographic Details
Main Authors: Sarah E Kelly, Altomare Di Benedetto, Adelaide Greco, Candace M Howard, Vincent E Sollars, Donald A Primerano, Jagan V Valluri, Pier Paolo Claudio
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2010-04-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC2851647?pdf=render