Dietary chlorogenic acid ameliorates oxidative stress and improves endothelial function in diabetic mice via Nrf2 activation

Objectives Chlorogenic acid (CGA) is an antioxidant dietary factor. We investigated the effects of CGA on endothelial cell dysfunction in diabetic mice and the mechanistic role of nuclear factor erythroid-related factor 2 (Nrf2) in the antioxidant effect of CGA. Methods Diabetic (db/db) mice were fe...

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Bibliographic Details
Main Authors: Dan Wang, Jixin Hou, Jindong Wan, Yi Yang, Sen Liu, Xiaoqing Li, Wenzhang Li, Xiaozhen Dai, Peng Zhou, Weihua Liu, Peijian Wang
Format: Article
Language:English
Published: SAGE Publishing 2021-01-01
Series:Journal of International Medical Research
Online Access:https://doi.org/10.1177/0300060520985363