A Central Role for TRPM4 in Ca<sup>2+</sup>-Signal Amplification and Vasoconstriction

A Central Role for TRPM4 in Ca<sup>2+</sup>-Signal Amplification and Vasoconstriction

Transient receptor potential melastatin-4 (TRPM4) is activated by an increase in intracellular Ca<sup>2+</sup> concentration and is expressed on smooth muscle cells (SMCs). It is implicated in the myogenic constriction of cerebral arteries. We hypothesized that TRPM4 has a general role i...

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Bibliographic Details
Main Authors: Tamás Csípő, Ágnes Czikora, Gábor Á. Fülöp, Hajnalka Gulyás, Ibolya Rutkai, Enikő Pásztorné Tóth, Róbert Pórszász, Andrea Szalai, Kata Bölcskei, Zsuzsanna Helyes, Erika Pintér, Zoltán Papp, Zoltán Ungvári, Attila Tóth
Format: Article
Language:English
Published: MDPI AG 2022-01-01
Series:International Journal of Molecular Sciences
Subjects:
transient receptor potential
transient receptor potential melastatin-4
blood pressure regulation
vascular smooth muscle
Ca<sup>2+</sup> signaling
Online Access:https://www.mdpi.com/1422-0067/23/3/1465

Internet

https://www.mdpi.com/1422-0067/23/3/1465

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