Xanthine oxidase inhibition study of isolated secondary metabolites from Dolichandrone spathacea (Bignoniaceae): In vitro and in silico approach

Xanthine oxidase inhibition study of isolated secondary metabolites from Dolichandrone spathacea (Bignoniaceae): In vitro and in silico approach

Xanthine oxidase (XO) has been widely recognized as a pivotal enzyme in developing hyperuricemia, primarily contributing to the excessive production of uric acid during purine metabolism in the liver. One of the standard treatment approaches involves reducing uric acid levels by inhibiting XO activi...

Full description

Bibliographic Details
Main Authors: Dang-Khoa Nguyen, Ta-Wei Liu, Su-Jung Hsu, Quoc-Dung Tran Huynh, Truc-Ly Thi Duong, Man-Hsiu Chu, Yun-Han Wang, Thanh-Hoa Vo, Ching-Kuo Lee
Format: Article
Language:English
Published: Elsevier 2024-04-01
Series:Saudi Pharmaceutical Journal
Subjects:
Dolichandrone spathacea
Hyperuricemia
Phytochemicals
Xanthine oxidase inhibitors
Enzyme kinetics
Molecular docking
Online Access:http://www.sciencedirect.com/science/article/pii/S1319016424000306

Internet

http://www.sciencedirect.com/science/article/pii/S1319016424000306

Similar Items