Cdk5 drives formation of heterogeneous pancreatic neuroendocrine tumors

Cdk5 drives formation of heterogeneous pancreatic neuroendocrine tumors

Abstract Pancreatic neuroendocrine tumors (PanNETs) are a heterogeneous population of neoplasms that arise from hormone-secreting islet cells of the pancreas and have increased markedly in incidence over the past four decades. Non-functional PanNETs, which occur more frequently than hormone-secretin...

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Bibliographic Details
Main Authors: Angela M. Carter, Nilesh Kumar, Brendon Herring, Chunfeng Tan, Rachael Guenter, Rahul Telange, Wayne Howse, Fabrice Viol, Tyler R. McCaw, Hayden H. Bickerton, Priyanka Gupta, Frank Gillardon, Eugene A. Woltering, Deepti Dhall, John Totenhagen, Ronadip R. Banerjee, Elizabeth M. Kurian, Sushanth Reddy, Herbert Chen, Joerg Schrader, J. Bart Rose, M. Shahid Mukhtar, James A. Bibb
Format: Article
Language:English
Published: Nature Publishing Group 2021-12-01
Series:Oncogenesis
Online Access:https://doi.org/10.1038/s41389-021-00372-5

Internet

https://doi.org/10.1038/s41389-021-00372-5

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