Low androgen signaling rescues genome integrity with innate immune response by reducing fertility in humans

Abstract Development of the gonads under complex androgen regulation is critical for germ cells specification. In this work we addressed the relationship between androgens and genomic integrity determining human fertility. We used different study groups: individuals with Differences of Sex Developme...

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Bibliographic Details
Main Authors: J. Zimmer, L. Mueller, P. Frank-Herrmann, J. Rehnitz, J. E. Dietrich, M. Bettendorf, T. Strowitzki, M. Krivega
Format: Article
Language:English
Published: Nature Publishing Group 2024-01-01
Series:Cell Death and Disease
Online Access:https://doi.org/10.1038/s41419-023-06397-5