UV Protection in the Cornea: Failure and Rescue

Ultraviolet (UV) irradiation induces DNA lesions in all directly exposed tissues. In the human body, two tissues are chronically exposed to UV: the skin and the cornea. The most frequent UV-induced DNA lesions are cyclobutane pyrimidine dimers (CPDs) that can lead to apoptosis or induce tumorigenesi...

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Bibliographic Details
Main Authors: Thomas Volatier, Björn Schumacher, Claus Cursiefen, Maria Notara
Format: Article
Language:English
Published: MDPI AG 2022-02-01
Series:Biology
Subjects:
Online Access:https://www.mdpi.com/2079-7737/11/2/278