To the Gut Microbiome and Beyond: The Brain-First or Body-First Hypothesis in Parkinson’s Disease

There is continued debate regarding Parkinson’s disease etiology and whether it originates in the brain or begins in the gut. Recently, evidence has been provided for both, with Parkinson’s disease onset presenting as either a “body-first” or “brain-first” progression. Most research indicates those...

Full description

Bibliographic Details
Main Authors: Nathan D. Nuzum, Amy Loughman, Ewa A. Szymlek-Gay, Wei-Peng Teo, Ashlee M. Hendy, Helen Macpherson
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-03-01
Series:Frontiers in Microbiology
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fmicb.2022.791213/full