Role of matrix metalloprotease-2 and MMP-9 in experimental lung fibrosis in mice

Role of matrix metalloprotease-2 and MMP-9 in experimental lung fibrosis in mice

Abstract Background Idiopathic pulmonary fibrosis (IPF) is a diffuse parenchymal lung disease characterized by exuberant deposition of extracellular matrix (ECM) proteins in the lung interstitium, which contributes to substantial morbidity and mortality in IPF patients. Matrix metalloproteinases (MM...

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Bibliographic Details
Main Authors: Tina Bormann, Regina Maus, Jennifer Stolper, Meritxell Tort Tarrés, Christina Brandenberger, Dirk Wedekind, Danny Jonigk, Tobias Welte, Jack Gauldie, Martin Kolb, Ulrich A. Maus
Format: Article
Language:English
Published: BMC 2022-07-01
Series:Respiratory Research
Subjects:
Gelatinase
IPF
Lung
Matrix metalloproteases
Online Access:https://doi.org/10.1186/s12931-022-02105-7

Internet

https://doi.org/10.1186/s12931-022-02105-7

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