Downregulation of TAB182 promotes cancer stem-like cell properties and therapeutic resistance in triple-negative breast cancer cells

Abstract TAB182 participates in DNA damage repair and radio-/chemosensitivity regulation in various tumors, but its role in tumorigenesis and therapeutic resistance in breast cancer remains unclear. In the current paper, we observed that triple-negative Breast Cancer (TNBC), a highly aggressive type...

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Bibliographic Details
Main Authors: Huan He, Shaozheng Wang, Wen Zhang, Shanshan Gao, Hua Guan, Pingkun Zhou
Format: Article
Language:English
Published: BMC 2023-11-01
Series:BMC Cancer
Subjects:
Online Access:https://doi.org/10.1186/s12885-023-11552-4