LC-MS-BASED METABOLOMICS OF XENOBIOTIC-INDUCED TOXICITIES

Xenobiotic exposure, especially high-dose or repeated exposure of xenobiotics, can elicit detrimental effects on biological systems through diverse mechanisms. Changes in metabolic systems, including formation of reactive metabolites and disruption of endogenous metabolism, are not only the common c...

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Bibliographic Details
Main Authors: Chi Chen, Sangyub Kim
Format: Article
Language:English
Published: Elsevier 2013-01-01
Series:Computational and Structural Biotechnology Journal
Online Access:http://www.sciencedirect.com/science/article/pii/S2001037014600519