Chemosensitizing effect of neferine on cisplatin-resistant colorectal cancer: Identification of potential candidate genes and pathways through whole transcriptome profiling

Chemosensitizing effect of neferine on cisplatin-resistant colorectal cancer: Identification of potential candidate genes and pathways through whole transcriptome profiling

Background: Cisplatin drug resistance is a serious impediment for the therapeutic success against platinum-based chemotherapy in several cancers. Neferine, a bisbenzylisoquinoline alkaloid from Nelumbo nucifera is an effective anticancer agent which has shown potential to reverse the chemo-resistanc...

Full description

Bibliographic Details
Main Authors: Bharath Somasundram, Prasath Manogaran, Madavan Vasudevan, Vijaya Padma Viswanadha
Format: Article
Language:English
Published: Elsevier 2022-08-01
Series:Phytomedicine Plus
Subjects:
Colorectal cancer
Cisplatin
DNA repair
Neferine
RNA sequencing
Online Access:http://www.sciencedirect.com/science/article/pii/S2667031322000823

Internet

http://www.sciencedirect.com/science/article/pii/S2667031322000823

Similar Items