Interleukin-22 Attenuated Renal Tubular Injury in Aristolochic Acid Nephropathy via Suppressing Activation of NLRP3 Inflammasome

Interleukin-22 Attenuated Renal Tubular Injury in Aristolochic Acid Nephropathy via Suppressing Activation of NLRP3 Inflammasome

Aristolochic acid nephropathy (AAN), as a rapidly progressive interstitial nephropathy due to excessive ingestion of aristolochia herbal medications, has recently raised considerable concerns among clinicians and researchers as its underlying pathogenic mechanisms are largely unclear. In the current...

Full description

Bibliographic Details
Main Authors: Shaofei Wang, Jiajun Fan, Xiaobin Mei, Jingyun Luan, Yubin Li, Xuyao Zhang, Wei Chen, Yichen Wang, Guangxun Meng, Dianwen Ju
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-09-01
Series:Frontiers in Immunology
Subjects:
IL-22
aristolochic acid nephropathy
NLRP3 inflammasome
tubular injury
renal function
Online Access:https://www.frontiersin.org/article/10.3389/fimmu.2019.02277/full

Internet

https://www.frontiersin.org/article/10.3389/fimmu.2019.02277/full

Similar Items