QKL injection ameliorates Alzheimer's disease-like pathology by regulating expression of RAGE

QKL injection ameliorates Alzheimer's disease-like pathology by regulating expression of RAGE

The onset of Alzheimer's disease is related to neuron damage caused by massive deposition of Aβ in the brain. Recent studies suggest that excessive Aβ in the brain mainly comes from peripheral blood, and BBB is the key to regulate Aβ in and out of the brain. In this study, we explored the patho...

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Bibliographic Details
Main Authors: Jinfang Dou, Xin'ai Zhang, Chaoqun Hu, Yuqian Gao, Yue Zhao, Murong Hei, Zhimiao Wang, Nan Guo, Haiyan Zhu
Format: Article
Language:English
Published: Elsevier 2024-06-01
Series:Experimental Gerontology
Subjects:
Alzheimer's disease
β-Amyloid
QKL injection
Receptor for advanced glycation end products
Network pharmacology
Molecular docking
Online Access:http://www.sciencedirect.com/science/article/pii/S0531556524000640

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http://www.sciencedirect.com/science/article/pii/S0531556524000640

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