Alternative pre-mRNA splicing as a mechanism for terminating Toll-like Receptor signaling

Alternative pre-mRNA splicing as a mechanism for terminating Toll-like Receptor signaling

While inflammation induced by Toll-like receptor (TLR) signaling is required to combat infection, persistent inflammation can damage host tissues and contribute to a myriad of acute and chronic inflammatory disorders. Thus, it is essential not only that TLR signaling be activated in the presence of...

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Bibliographic Details
Main Authors: Frank Fang Yao Lee, Scott Alper
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-12-01
Series:Frontiers in Immunology
Subjects:
TLR signaling
innate immunity
inflammation
pre-mRNA splicing
spliceosome
RNA binding protein
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2022.1023567/full

Internet

https://www.frontiersin.org/articles/10.3389/fimmu.2022.1023567/full

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