Obeticholic Acid—A Pharmacological and Clinical Review

Obeticholic Acid—A Pharmacological and Clinical Review

Obeticholic acid (OCA) or 6-alpha-ethyl-chenodeoxycholic acid is a semisynthetic modified bile acid derivative that acts on the farnesoid X receptor (FXR) as an agonist with a higher potency than bile acid. The FXR is a nuclear receptor highly expressed in the liver and small intestine and regulates...

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Bibliographic Details
Main Authors: Caezaan Keshvani, Jonathan Kopel, Hemant Goyal
Format: Article
Language:English
Published: MDPI AG 2023-02-01
Series:Future Pharmacology
Subjects:
obeticholic acid
non-alcoholic fatty liver disease
metabolic syndrome
biliary cirrhosis
primary biliary cholangitis
non-alcoholic steatohepatitis
Online Access:https://www.mdpi.com/2673-9879/3/1/17

Internet

https://www.mdpi.com/2673-9879/3/1/17

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