Optic nerve thinning and neurosensory retinal degeneration in the rTg4510 mouse model of frontotemporal dementia

Optic nerve thinning and neurosensory retinal degeneration in the rTg4510 mouse model of frontotemporal dementia

Abstract Visual impairments, such as difficulties in reading and finding objects, perceiving depth and structure from motion, and impaired stereopsis, have been reported in tauopathy disorders, such as frontotemporal dementia (FTD). These impairments however have been previously attributed to cortic...

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Bibliographic Details
Main Authors: Ian F. Harrison, Rozalind Whitaker, Pietro Maria Bertelli, James M. O’Callaghan, Lajos Csincsik, Martina Bocchetta, Da Ma, Alice Fisher, Zeshan Ahmed, Tracey K. Murray, Michael J. O’Neill, Jonathan D. Rohrer, Mark F. Lythgoe, Imre Lengyel
Format: Article
Language:English
Published: BMC 2019-01-01
Series:Acta Neuropathologica Communications
Subjects:
Tau
Frontotemporal dementia
Neurosensory retina
MRI
Online Access:http://link.springer.com/article/10.1186/s40478-018-0654-6

Internet

http://link.springer.com/article/10.1186/s40478-018-0654-6

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