A sensitive and rapid electrochemical biosensor for sEV-miRNA detection based on domino-type localized catalytic hairpin assembly

A sensitive and rapid electrochemical biosensor for sEV-miRNA detection based on domino-type localized catalytic hairpin assembly

Abstract Small extracellular–vesicule-associated microRNA (sEV-miRNA) is an important biomarker for cancer diagnosis. However, rapid and sensitive detection of low-abundance sEV-miRNA in clinical samples is challenging. Herein, a simple electrochemical biosensor that uses a DNA nanowire to localize...

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Bibliographic Details
Main Authors: Wenbin Li, Wen Wang, Shihua Luo, Siting Chen, Tingting Ji, Ningcen Li, Weilun Pan, Xiaohe Zhang, Xiaojing Wang, Ke Li, Ye Zhang, Xiaohui Yan
Format: Article
Language:English
Published: BMC 2023-09-01
Series:Journal of Nanobiotechnology
Subjects:
DNA nanowire
Catalyzed hairpin assembly
sEV-miRNAs
Early cancer diagnostics
Online Access:https://doi.org/10.1186/s12951-023-02092-x

Internet

https://doi.org/10.1186/s12951-023-02092-x

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