A flavonoid rich standardized extract of Glycyrrhiza glabra protects intestinal epithelial barrier function and regulates the tight-junction proteins expression

A flavonoid rich standardized extract of Glycyrrhiza glabra protects intestinal epithelial barrier function and regulates the tight-junction proteins expression

Abstract Background Intestinal epithelial barrier dysfunction predisposes to many gastrointestinal, metabolic, and psychological disorders. A flavonoid rich extract of Glycyrrhiza glabra (FREG) has previously been reported to possess anti-inflammatory, antioxidant, and antiulcer properties. Aim To i...

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Bibliographic Details
Main Authors: Sasi Kumar Murugan, Bharathi Bethapudi, Subramanian Raghunandhakumar, Divya Purusothaman, Muruganantham Nithyanantham, Deepak Mundkinajeddu, Muralidhar Srinivasaih Talkad
Format: Article
Language:English
Published: BMC 2022-02-01
Series:BMC Complementary Medicine and Therapies
Subjects:
Leaky gut
Glycyrrhiza glabra
Intestinal permeability
2,4,6-Trinitrobenzenesulfonic acid
TNF-alpha
Tight junction proteins
Online Access:https://doi.org/10.1186/s12906-021-03500-1

Internet

https://doi.org/10.1186/s12906-021-03500-1

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