Biopsy-derived oral keratinocytes – A model to potentially test for oral mucosa radiation sensitivity

Purpose: To establish stable in vitro growth of keratinocytes from very small biopsy specimens and successfully apply new test systems to determine their radiosensitivity. Materials and Methods: Oral mucosa biopsies (diameter: 1.7 mm) from 15 subjects were immobilized with custom-made cups onto cult...

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Bibliographic Details
Main Authors: A.R. Thomsen, C. Aldrian, B. Luka, S. Hornhardt, M. Gomolka, S. Moertl, J. Hess, H. Zitzelsberger, T. Heider, N. Schlueter, S. Rau, B. Monroy Ordonez, H. Schäfer, G. Rücker, M. Henke, Katharina Huber
Format: Article
Language:English
Published: Elsevier 2022-05-01
Series:Clinical and Translational Radiation Oncology
Online Access:http://www.sciencedirect.com/science/article/pii/S2405630822000209